How to Fix Rufus Error: The Device is in Use by Another Process (Error 006564)

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Are you encountering the frustrating Rufus Error: The Device is in Use by Another Process (Error 006564) while trying to create a bootable USB drive? Don’t worry, you’re not alone. This error message can be quite perplexing, leaving you wondering how to resolve it.

Error 006564

In this article, we will walk you through the steps to fix the Rufus Error: The Device is in Use by Another Process (Error 006564). Whether you’re a tech-savvy individual or a beginner, our easy-to-follow instructions will help you overcome this obstacle and successfully create your bootable USB drive.

We understand the importance of having a reliable bootable USB drive, especially when you need to install operating systems or run diagnostics on your computer. That’s why it’s crucial to address this error promptly and efficiently.

By following our troubleshooting tips, you’ll be able to troubleshoot and resolve the Rufus Error: The Device is in Use by Another Process (Error 006564) effectively. Say goodbye to the frustration and continue with your USB creation process seamlessly. Let’s get started and get your bootable USB drive up and running in no time.

Understanding the “Device is in Use by Another Process” error

The Rufus Error: The Device is in Use by Another Process (Error 006564) occurs when Rufus, a popular tool for creating bootable USB drives, encounters a conflict with another process or application using the same device. This error prevents Rufus from gaining exclusive access to the USB drive, resulting in the inability to proceed with the USB creation process.

To fix this error, it’s essential to understand the common causes behind it. By identifying the root cause, you can implement the appropriate troubleshooting steps and get your bootable USB drive working without any issues.

Common causes of the error

There are several reasons why you might encounter the Rufus Error: The Device is in Use by Another Process (Error 006564). Let’s explore some of the common causes:

  1. Background processes: Other applications or processes running on your computer might be accessing the USB drive, preventing Rufus from gaining exclusive access. These processes can include antivirus software, backup utilities, or even Windows services.
  2. Faulty USB connection: A loose or faulty USB connection can trigger the error. If the USB device is not properly connected to your computer, Rufus may encounter difficulties in accessing it exclusively.
  3. Outdated Rufus version: Using an outdated version of Rufus can sometimes lead to conflicts and errors. It’s crucial to keep your Rufus software up to date to ensure compatibility with your operating system and avoid potential issues.
  4. Outdated USB drivers: Similarly, outdated USB drivers on your computer can cause conflicts with Rufus. Keeping your USB drivers updated is essential for smooth operation and compatibility with Rufus.

Now that we have a better understanding of the potential causes behind the error, let’s dive into the troubleshooting steps to resolve it.

Troubleshooting steps for fixing the error

To fix the Rufus Error: The Device is in Use by Another Process (Error 006564), you can follow these troubleshooting steps. Each step addresses a specific potential cause of the error, helping you narrow down and resolve the issue effectively.

  1. Right-click on the Rufus executable file.
  2. Select “Run as administrator” from the context menu.
  3. If prompted for confirmation, click “Yes” to proceed.

When creating a bootable disk, the new version of operating system of Windows, ubunutu, Linux, all uses GUID Partition Table (GPT). If you choose the Master Boot Record (MBR) to built the USB bootable device, you will encounter the error The Device is in Use by Another Process (Error 006564). To fix this error always choose GUID Partition Table (GPT).

The Device is in Use by Another Process
The Device is in Use by Another Process (Error 006564)

Key differences between MBR and GPT

While both MBR and GPT serve the purpose of organizing and booting from a disk, there are several key differences between the two.

  1. Partitioning Limitations: MBR has a limit of four primary partitions, or three primary partitions and one extended partition. GPT, on the other hand, can support up to 128 partitions by default, with the possibility of even more.
  2. Disk Size: MBR supports disks up to 2 terabytes in size, while GPT can handle much larger disks, up to 9.4 zettabytes.
  3. Boot Compatibility: MBR is compatible with both legacy BIOS and newer UEFI systems. GPT is primarily designed for UEFI systems, although it can also be used with legacy BIOS through the Compatibility Support Module (CSM).
  4. Data Integrity: GPT includes a redundant copy of the partitioning information at the end of the disk, which provides better protection against data loss in case of disk corruption.


Understanding the differences between MBR and GPT is crucial when creating a bootable disk. While MBR is compatible with most systems and offers simplicity, GPT provides more flexibility, scalability, and data integrity. By following the appropriate steps, you can create a bootable disk using either MBR or GPT depending on your specific needs. Remember to consider factors such as disk size, compatibility, and data protection when choosing between the two partitioning schemes.

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